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ExAnteOptifoldby ExAnte Labs
Sequence-based research scoring. This workspace does not run a folding model.

Score a protein sequence.

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Sequence

100–600 residues

One sequence, using the 20 standard amino-acid letters.

350 residues
The calculation
S=0.67z(H)+0.33z(D)S = 0.67\,z(H) + 0.33\,z(-D)

H is mean Kyte–Doolittle hydropathy. D is the fraction of A, R, G, Q, S, P, E and K. Both use the frozen development-set scaling.

Formula and source details

Combined sequence score

Calculate to view the named secondary research score.

Mean hydropathy, HScaled H: —
Composition fraction, D

Frozen primary screen

The primary D ≤ 0.5641 rule remains separate from the combined score.

Amino-acid composition